You Searched For: Thio-NAD

Catalog Number: (BOSSBS-9456R-FITC)

Supplier: Bioss

Description: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-9456R-A350)

Supplier: Bioss

Description: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

UOM: 1 * 100 µl

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Catalog Number: (45402.4I)

Supplier: Thermo Fisher Scientific

Description: Applications: Diagnostics and cofactor regeneration of NAD(P)H in reductive processes.

UOM: 1 * 1 KU

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Catalog Number: (BOSSBS-7537R-HRP)

Supplier: Bioss

Description: Acts both as NAD-dependent protein ADP-ribosyl transferase and NAD-dependent protein deacetylase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Down-regulates insulin secretion.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1568R-CY3)

Supplier: Bioss

Description: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-0273R-CY3)

Supplier: Bioss

Description: icotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Fisfatin) Catalyzes the condensation of nicotinamide with5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues. Subcellular Location is in Cytoplasm. Belongs to the NAPRTase family.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-0273R-CY5)

Supplier: Bioss

Description: icotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Fisfatin) Catalyzes the condensation of nicotinamide with5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues. Subcellular Location is in Cytoplasm. Belongs to the NAPRTase family.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-0273R-A555)

Supplier: Bioss

Description: icotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Fisfatin) Catalyzes the condensation of nicotinamide with5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues. Subcellular Location is in Cytoplasm. Belongs to the NAPRTase family.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1901R-CY3)

Supplier: Bioss

Description: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1568R-CY5.5)

Supplier: Bioss

Description: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1568R-PE)

Supplier: Bioss

Description: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-7693R)

Supplier: Bioss

Description: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-2388R-A680)

Supplier: Bioss

Description: Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-4834R-CY5.5)

Supplier: Bioss

Description: Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1901R)

Supplier: Bioss

Description: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).

UOM: 1 * 100 µl

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Catalog Number: (BOSSBS-1901R-CY7)

Supplier: Bioss

Description: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).

UOM: 1 * 100 µl

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