You Searched For: Trichloro(phenyl)silane


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Description: Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.
Catalog Number: BOSSBS-8177R-FITC
UOM: 1 * 100 µl
Supplier: Bioss


Description: P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.
Catalog Number: BOSSBS-0534R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Catalog Number: BOSSBS-1610R-HRP
UOM: 1 * 100 µl
Supplier: Bioss


Description: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Catalog Number: BOSSBS-1610R-A680
UOM: 1 * 100 µl
Supplier: Bioss


Description: Erastin is a compound that interacts with VDAC blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers It is also a ferroptosis inducer.
Catalog Number: APOSBISN0097-1MG
UOM: 1 * 1 mg
Supplier: Apollo Scientific


Description: A potent and selective inhibitor of Cdc25 phosphatase (Ki's for Cdc25A, B and C are 32, 96 and 40 nM respectively). NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.
Catalog Number: ENZOBMLEI3090005
UOM: 1 * 5 mg
Supplier: ENZO LIFE SCIENCES


Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Catalog Number: BOSSBS-8191R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
Catalog Number: BOSSBS-1049R-CY7
UOM: 1 * 100 µl
Supplier: Bioss


Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
Catalog Number: BOSSBS-1235R-A680
UOM: 1 * 100 µl
Supplier: Bioss


Description: This blot contains two protein lanes, a protein marker lane and a lane with one GenLysate™ sample. After the proteins are resolved, they are transferred to a PVDF membrane using Western Transfer Buffer. The blots are ready to be blocked and probed with the antibodies of choice.
Catalog Number: TB23
UOM: 1 * 1 items
Supplier: G-Biosciences


Description: This blot contains two protein lanes, a protein marker lane and a lane with one GenLysate™ sample. After the proteins are resolved, they are transferred to a PVDF membrane using Western Transfer Buffer. The blots are ready to be blocked and probed with the antibodies of choice.
Catalog Number: TB27
UOM: 1 * 1 items
Supplier: G-Biosciences


Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
Catalog Number: BOSSBS-1049R-A647
UOM: 1 * 100 µl
Supplier: Bioss


Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
Catalog Number: BOSSBS-1049R-A555
UOM: 1 * 100 µl
Supplier: Bioss


Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Catalog Number: BOSSBS-8191R-A350
UOM: 1 * 100 µl
Supplier: Bioss


Description: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Catalog Number: BOSSBS-0792R-HRP
UOM: 1 * 100 µl
Supplier: Bioss


Description: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Catalog Number: BOSSBS-0792R-FITC
UOM: 1 * 100 µl
Supplier: Bioss


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