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Image Unavailable-BOSSBS-5292R-A555

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-5292R-A555)
Supplier: Bioss
Description: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5293R-A350

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-5293R-A350)
Supplier: Bioss
Description: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-13451.36

Potassium hydroxide ≥85% ACS (max. 2% K₂CO₃)

Supplier: Thermo Fisher Scientific
Description: Potassium hydroxide ≥85% ACS (max. 2% K₂CO₃)

MSDS Certificates

Image Unavailable-A13146.14

2-Hydroxyisobutyric acid, (max. 2% H₂O) 99% (dry weight)

Supplier: Thermo Fisher Scientific
Description: 2-Hydroxyisobutyric acid, (max. 2% H₂O) 99% (dry weight)

MSDS Certificates

Product Image-SENA0096647495101

Temp only module, module for AiroSensor X ER 20-20-43 with external temperature

Catalog Number: (SENA0096647495101)
Supplier: SenseAnywhere
Description: The Temp Only Module from SenseAnywhere is a small connector with enormous potential. The module can accurately monitor temperatures from −40 to +70 °C. The powerful Temp Only module has a swift response time because the sensor is exposed to the environment directly and has minimal material around it.
UOM: 1 * 1 items
Product Image-BWTEXT-SS-1

Accessories for gas alert max XT II

Supplier: BW TECHNOLOGIES
Description: Accessory for gas detection, For: Max XT II, Replacement MICROpeL combustible (LEL) sensor

Product Image-568-0876

Inline PTFE gas filters, Wafergard® MAX

Supplier: ENTEGRIS
Description: These filters are compatible with high purity gases as well as general nitrogen and CDA applications. Available in Bronze and Silver performance levels, they are specifically designed for high flow and low delta pressure applications and provide ultimate process protection by removing contaminants that could affect process quality.

Image Unavailable-33302.22

Charcoal activated, powder (total ash max 4%)

Supplier: Thermo Fisher Scientific
Description: Charcoal activated, powder (total ash max 4%)

MSDS Certificates

Image Unavailable-B23504.36

Troclosene sodium, (max. 3% H₂O) 97% (dry weight)

Supplier: Thermo Fisher Scientific
Description: Troclosene sodium, (max. 3% H₂O) 97% (dry weight)

MSDS Certificates

Image Unavailable-A10958.0E

1,4-Naphthoquinone, (max. 5% H₂O) 97+% (dry weight)

Supplier: Thermo Fisher Scientific
Description: 1,4-Naphthoquinone, (max. 5% H₂O) 97+% (dry weight)

MSDS Certificates

Image Unavailable-B24523.36

Mucochloric acid, (max. 4% H₂O) 99% (dry weight)

Catalog Number: (B24523.36)
Supplier: Thermo Fisher Scientific
Description: Mucochloric acid, (max. 4% H₂O) 99% (dry weight)
UOM: 1 * 500 g

MSDS Certificates


Product Image-BARN600078

Test tube racks and holders for incubating shakers, MaxQ™, Barnstead

Supplier: Thermo Fisher Scientific
Description: Rack, Test tube, For tube Ø: 10 - 13 mm, No. of holes: 72, For tubes: 3 - 7 ml

Product Image-USBID1150-05A-HRP

Anti-DAXX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (USBID1150-05A-HRP)
Supplier: US Biological
Description: Anti-DAXX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 200 µl
Image Unavailable-BOSSBS-5288R-A647

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-5288R-A647)
Supplier: Bioss
Description: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12984R-A555

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-12984R-A555)
Supplier: Bioss
Description: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED3 protease family. A novel DD containing molecule was recently cloned from mouse, human and monkey and designated Daxx. Daxx is a death domain containing important intermediate in the Fas mediated apoptosis. Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N terminal kinase (JNK) pathway. It is widely expressed in fetal and adult human and mouse tissue, indicating its important function in Fas signaling pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1975R-A647

Anti-DAXX Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalog Number: (BOSSBS-1975R-A647)
Supplier: Bioss
Description: Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intrinsic E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal degradation. Upon DNA damage, its association with MDM2 and USP7 is disrupted, resulting in increased MDM2 autoubiquitination and consequently, MDM2 degradation, which leads to TP53 stabilization. Proposed to mediate activation of the JNK pathway and apoptosis via MAP3K5 in response to signaling from TNFRSF6 and TGFBR2. Interaction with HSPB1/HSP27 may prevent interaction with TNFRSF6 and MAP3K5 and block DAXX-mediated apoptosis. In contrast, in lymphoid cells JNC activation and TNFRSF6-mediated apoptosis may not involve DAXX. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Down-regulates basal and activated transcription. Seems to act as a transcriptional corepressor and inhibits PAX3 and ETS1 through direct protein-protein interaction. Modulates PAX5 activity. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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