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Catalog Number: (PRSI92-428)
Supplier: ProSci Inc.
Description: Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
UOM: 1 * 50 µG


Catalog Number: (PRSI90-223)
Supplier: ProSci Inc.
Description: RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of breast cancer.
UOM: 1 * 10 µG


Catalog Number: (PRSI91-068)
Supplier: ProSci Inc.
Description: Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
UOM: 1 * 50 µG


Catalog Number: (PRSI91-842)
Supplier: ProSci Inc.
Description: Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.
UOM: 1 * 50 µG


Catalog Number: (PRSI4261P)
Supplier: ProSci Inc.
Description: MICA peptide is used for blocking the activity of MICA antibody.
UOM: 1 * 50 µG


Catalog Number: (PRSI3623P)
Supplier: ProSci Inc.
Description: CRMP1 peptide is used for blocking the activity of CRMP1 antibody.
UOM: 1 * 50 µG


Catalog Number: (PRSI40-595)
Supplier: ProSci Inc.
Description: The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.
UOM: 1 * 100 µG


Catalog Number: (PRSI3909P)
Supplier: ProSci Inc.
Description: Avian influenza hemagglutinin 2 peptide is used for blocking activity of avian influenza hemagglutinin 2 antibody. It usually blocks antibody activity completely in ELISA assays by incubating peptide with equal volume of antibody for 30 min at 37 °C antibody.
UOM: 1 * 50 µG


Catalog Number: (PRSI3477P)
Supplier: ProSci Inc.
Description: Mcl-1 peptide is used for blocking the activity of Mcl-1 antibody.
UOM: 1 * 50 µG


Catalog Number: (PRSI7249P)
Supplier: ProSci Inc.
Description: 16 amino acid peptide near the carboxy terminus of human RRAS2.
UOM: 1 * 50 µG


Catalog Number: (PRSI5071P)
Supplier: ProSci Inc.
Description: PCDH12 peptide is used for blocking the activity of PCDH12 antibody.
UOM: 1 * 50 µG


Catalog Number: (PRSI91-568)
Supplier: ProSci Inc.
Description: Pancreatic Lipase-Related Protein 1 (PNLIPRP1) belongs to the Lipase family within the AB hydrolase superfamily. PNLIPRP1 is a secreted protein and contains one PLAT domain. PNLIPRP1 is involved in lipid metabolic process, acting as a negative regulator of pancreatic lipase activity by competing with pancreatic lipase for colipase occupancy. PNLIPRP1 may play a role in inhibiting dietary triglyceride digestion, but it lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters.
UOM: 1 * 50 µG


Catalog Number: (PRSI90-219)
Supplier: ProSci Inc.
Description: Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibits the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the 'annexin V affinity assay' to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
UOM: 1 * 100 Tests


Catalog Number: (PRSI1129P)
Supplier: ProSci Inc.
Description: NIK peptide is used for blocking the activity of NIK antibody.
UOM: 1 * 50 µG


Catalog Number: (PRSI91-425)
Supplier: ProSci Inc.
Description: Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
UOM: 1 * 50 µG


Catalog Number: (PRSI6487P)
Supplier: ProSci Inc.
Description: EI24 peptide is used for blocking the activity of EI24 antibody.
UOM: 1 * 50 µG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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