Anti-CD16/CD32 Rat Monoclonal Antibody [clone: 2.4G2] (FITC)

Supplier: STEMCELL Technologies
60161FI 60161FI.1
STMC60161FIEA 246 EUR
STMC60161FI STMC60161FI.1
Anti-CD16/CD32 Rat Monoclonal Antibody [clone: 2.4G2] (FITC)
Antibodies
Rat monoclonal IgG2b antibody against mouse CD16/CD32, FITC-conjugated.

  • Dendritic cells
  • Granulocytes
  • Subsets
  • Macrophages
  • Monocytes
  • Myeloid cells
  • Nk cells
  • T cells
  • T cells Other Subsets

The 2.4G2 antibody reacts with a shared epitope of Fc-gamma receptors CD16 (FcRIII) and CD32 (FcRII) in the mouse. CD16 and CD32 are low affinity receptors for the Fc portion of IgG, with CD32 having a higher affinity for IgG aggregates and immune complexes. CD16 and CD32 are expressed on B cells, monocytes, macrophages, NK cells, neutrophils, granulocytes, mast cells, and dendritic cells. The binding of immunoglobulins to Fc receptors is involved in multiple immunological functions, including phagocytosis, cytotoxocity, and the modulation of immune responses. The 2.4G2 antibody blocks the interaction between IgG and CD16 or CD32, and therefore is used as a pre-treatment to minimize non-specific binding of antibodies to FcR-bearing cells in applications such as flow cytometry, cell sorting, and immunofluorescence.

Caution: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type: Anti-CD16/CD32 Rat Monoclonal Antibody [clone: 2.4G2] (FITC)
Antigen: CD16/CD32
Clonality: Monoclonal
Clone: 2.4G2
Conjugation: FITC
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity: Mouse
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