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Image Unavailable-BOSSBS-0738R-A750

Anti-Livin Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (BOSSBS-0738R-A750)
Supplier: Bioss
Description: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLL1370005

WEB-2086 ≥98% (by HPLC)

Catalog Number: (ENZOBMLL1370005)
Supplier: ENZO LIFE SCIENCES
Description: PAF receptor antagonist. Inhibits PAF-induced human platelet and neutrophil aggregation in vitro (IC50=0.17 and 0.36µM respectively). In vivo it dose dependently blocks eosinophil activation and displays antiallergic and anti-inflammatory activity in various models. Induces differentiation and triggers apoptosis and in a variety of cell lines.
UOM: 1 * 5 mg
Image Unavailable-ORIGTS422909P5

Human ERBB2

Catalog Number: (ORIGTS422909P5)
Supplier: OriGene
Description: HEK293T cells were transiently transfected with TrueORF cDNA plasmid. Transfected cells were cultured for 48 hrs. After harvesting, the cultured cells were fixed in formalin and dehydrated before embedding in paraffin. 5 µm sections of the FFPE cell pellet blocks are cut and mounted on positively charged SuperFrost slides.
UOM: 1 * 1 KIT
Image Unavailable-ORIGTS412583P5

Human ERBB2

Catalog Number: (ORIGTS412583P5)
Supplier: OriGene
Description: HEK293T cells were transiently transfected with TrueORF cDNA plasmid. Transfected cells were cultured for 48 hrs. After harvesting, the cultured cells were fixed in formalin and dehydrated before embedding in paraffin. 5 µm sections of the FFPE cell pellet blocks are cut and mounted on positively charged SuperFrost slides.
UOM: 1 * 1 KIT
Image Unavailable-BOSSBS-1049R-HRP

Anti-CHRNA7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-1049R-HRP)
Supplier: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-A555

Anti-HYAL1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-1235R-A555)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-A488

Anti-HYAL1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-1235R-A488)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Product Image-BRDY311937

Brady® FR22 RFID Fixed Reader

Catalog Number: (BRDY311937)
Supplier: Brady
Description: The BRADY FR22 is the core device of a new approach for RFID fixed systems with wide communication options and a modular design. The FR22 is a critical building block for various track and trace and intelligent manufacturing solutions. It enables different use cases for different segments depending on which modules are attached to it.
UOM: 1 * 1 items
Image Unavailable-ENZOALX153064M005

Caveolin-1 scaffolding domain peptide

Supplier: ENZO LIFE SCIENCES
Description: Cell permeable peptide that blocks eNOS (NOS III) activity and cellular nitric oxide (NO) release in vitro and reduces inflammation and tumorigenesis in vivo. Caveolin-1 interacts with several lipid-modified signalling ligands, such as EGFR, eNOS, G-protein α-subunits, PKCα, H-Ras, and Src, via the C1-SD82-101 sequence.

Image Unavailable-BOSSBS-1346R-CY3

Anti-TRP73 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-1346R-CY3)
Supplier: Bioss
Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
UOM: 1 * 100 µl
Product Image-CAYM17493-1

NF-κB Inhibitor (SN50)

Supplier: Cayman Chemical
Description: A synthetic peptide corresponding to the nuclear localisation sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

Image Unavailable-BNCB0988-500

Anti-ICAM1 Mouse Monoclonal Antibody (Biotin) [clone: 1H4 or Wehi-CAM-1 or W-CAM-1]

Supplier: Biotium
Description: Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

Image Unavailable-BOSSBS-0738R-A350

Anti-BIRC7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-0738R-A350)
Supplier: Bioss
Description: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLCC1020500

L-Mimosine ≥98%

Catalog Number: (ENZOBMLCC1020500)
Supplier: ENZO LIFE SCIENCES
Description: A rare plant amino acid that reversibly blocks the cell cycle at G1-phase. Inhibits the hydroxylation of deoxyhypusine and thus inhibits eukaryote initiation factor 5-A (eIF5-A). Inhibitor of mammalian tyrosinase and dopamine β-hydroxylase. Also chelates iron via the kojic acid metal-binding domain. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism.
UOM: 1 * 500 mg
Image Unavailable-BOSSBS-8191R-A680

Anti-CSTP1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (BOSSBS-8191R-A680)
Supplier: Bioss
Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1049R-CY5

Anti-CHRNA7 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1049R-CY5)
Supplier: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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