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Image Unavailable-BOSSBS-1610R-A488

Anti-CK7 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-1610R-A488)
Supplier: Bioss
Description: Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-A350

Anti-HYAL1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-1235R-A350)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0792R-A555

Anti-SERPINB5 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Catalog Number: (BOSSBS-0792R-A555)
Supplier: Bioss
Description: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8191R-A488

Anti-CPPED1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalog Number: (BOSSBS-8191R-A488)
Supplier: Bioss
Description: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1049R-A350

Anti-CHRNA7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (BOSSBS-1049R-A350)
Supplier: Bioss
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1235R-FITC

Anti-HYAL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (BOSSBS-1235R-FITC)
Supplier: Bioss
Description: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth (By similarity). Overexpression of HYAL1 suppressed the growth rate of colon carcinoma cell tumors in an experimental model.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1346R-CY5

Anti-TRP73 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-1346R-CY5)
Supplier: Bioss
Description: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
UOM: 1 * 100 µl
Image Unavailable-ENZOBMLST3200100

Ono-RS-082 ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES
Description: Phospholipase A2 inhibitor (IC50=7 µM for purified guinea pig lung PLA2). Inhibits epinephrine-stimulated thromboxane production in human platelets (86% at 3.5µM). Also blocks insulin secretion in pancreatic islets in response to glucose. Disrupts membrane tubule-mediated reassembly and maintenance of the Golgi complex.

Product Image-S0900-100

Donor horse serum

Supplier: Biowest
Description: Donor horse serum is aseptically collected from herds of healthy animals inspected periodically by a licensed veterinarian. Applications for donor horse serum include mycoplasma contamination tests carried out on media, blocking agent and controls in immunoassays, culture of PC12 cells when combined with FBS.

MSDS

Product Image-BOSSBS-0792R

Anti-MASPIN Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-0792R)
Supplier: Bioss
Description: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8177R-CY3

Anti-KIF11 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-8177R-CY3)
Supplier: Bioss
Description: Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6385R-HRP

Anti-GAS1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-6385R-HRP)
Supplier: Bioss
Description: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY5

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (BOSSBS-0738R-CY5)
Supplier: Bioss
Description: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BNC470988-100

Anti-ICAM1 Mouse Monoclonal Antibody (CF647) [clone: 1H4 or Wehi-CAM-1 or W-CAM-1]

Supplier: Biotium
Description: Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

Image Unavailable-BNC680988-500

Anti-ICAM1 Mouse Monoclonal Antibody (CF568) [clone: 1H4 or Wehi-CAM-1 or W-CAM-1]

Supplier: Biotium
Description: Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).

Image Unavailable-BOSSBS-0534R-CY3

Anti-p19ARF Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (BOSSBS-0534R-CY3)
Supplier: Bioss
Description: P19ARF Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development.
UOM: 1 * 100 µl
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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