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Supplier: Biorbyt
Description: Anti-Hemoglobin alpha 1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI29-718)
Supplier: ProSci Inc.
Description: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
UOM: 1 * 50 µG


Catalog Number: (BOSSBS-0018M)
Supplier: Bioss
Description: Insulysin was identified nearly a century ago as an enzyme responsible for the degradation of insulin in cells, although the precise interactions between insulin and insulysin remain elusive. Human insulysin was cloned in 1988, and shown to be a 118 kDa protein that exists primarily as a homodimer, and perhaps also complexed with other molecules. The sequence is well conserved between humans, rats and mice, and the antibody recognizes these species. Insulysin is a metalloproteinase of the clan ME, family M16, which contains an active site HxxEH, a reversal of the canonical HExxH zinc binding motif. Considered a zinc metalloproteinase, the activity of insulysin can be blocked with EDTA or 1-10 phenanthroline. In addition to the active metalloproteinase domain, insulysin contains a second metalloproteinase site which is considered catalytically inactive, and is thought to assist in substrate binding. Insulysin is most closely related to the bacterial proteinase pitrilysin, (the human orthologue of which appears to be MPRP1) and the mammalian proteinsae nardilysin. Generally thought to be a cytoplasmic protein, insulysin has been isolated from many different tissues and cell lines, and can degrade intact insulin, insulin B chain, glucagon, denatured hemoglobin, alpha amyloid protein, TGF alpha and amylin. Recent work implicates insulysin in clearing beta amyloid plaques from the brain, and has generated much interest in Alzheimer’s disease research. The pH optimum for insulysin is basic, pH 8.5, which also distinguishes it from other metalloproteinases. Insulin degrading enzyme (IDE) has a preferential affinity for insulin such that the presence of insulin will inhibit IDE mediated degradation of other substrates. IDE degrades a variety of other peptides including atrial natriuretic peptide and amylin.
UOM: 1 * 100 µl


Catalog Number: (ANTIA10026-100)
Supplier: ANTIBODIES.COM
Description: Rabbit polyclonal antibody to Hemoglobin subunit zeta for WB with samples derived from human.
UOM: 1 * 100 µl

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Catalog Number: (ANTIA91546-100)
Supplier: ANTIBODIES.COM
Description: Anti-Hemoglobin subunit alpha Rabbit Polyclonal Antibody
UOM: 1 * 100 µl

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Supplier: VWR Seradigm
Description: Avantor® Seradigm South America origin FBS preserves more of the naturally-occurring growth factors that cells require to thrive, resulting in the highest possible quality sera for a price that fits your budget.
Catalog Number: (ABNOPAB29177)
Supplier: Abnova
Description: Chicken polyclonal antibody raised against native Human Hemoglobin with Biotin conjugation.
UOM: 1 * 100 µG


Catalog Number: (ABNOPAB29176)
Supplier: Abnova
Description: Chicken polyclonal antibody raised against native Human Hemoglobin.
UOM: 1 * 100 µG


Catalog Number: (ABNOMAB0030-M01)
Supplier: Abnova
Description: Mouse monoclonal antibody raised against glycosylated hemoglobin.
UOM: 1 * 100 µG


Catalog Number: (PRSIXW-7243)
Supplier: ProSci Inc.
Description: Haptoglobin, Mixed type. Haptoglobin combines with free plasma hemoglobin, prevent loss of iron through the kidneys and protect the kidneys from damage by hemoglobin, while making the hemoglobin accessible to degradative enzymes.
UOM: 1 * 50 µG


Supplier: VWR Seradigm
Description: Avantor Seradigm Select Grade FBS provides superior performance and consistency in cost-sensitive applications.

Catalog Number: (ABNOPAB29178)
Supplier: Abnova
Description: Chicken polyclonal antibody raised against native Human Hemoglobin with HRP conjugation.
UOM: 1 * 100 µG


Catalog Number: (PRSI55-335)
Supplier: ProSci Inc.
Description: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 400 µl

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Catalog Number: (BSBTA00233-1)
Supplier: Boster Bio
Description: Rabbit IgG polyclonal antibody for Hemoglobin subunit alpha(HBA1|HBA2) detection. Tested with WB, IHC-P in Human;Rat.
UOM: 1 * 100 µG


Catalog Number: (PRSI92-286)
Supplier: ProSci Inc.
Description: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.
UOM: 1 * 50 µG


Catalog Number: (USBIA0759-25)
Supplier: US Biological
Description: Anti-Actin, Cardiac, Fetal Mouse Monoclonal Antibody [clone: 5F152]
UOM: 1 * 50 µG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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