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Image Unavailable-SIAL718467-100G

Titanium(IV) oxide, Sigma-Aldrich®

Catalog Number: (SIAL718467-100G)
Supplier: Merck
Description: Titanium(IV) oxide, Sigma-Aldrich®
UOM: 1 * 100 g
Image Unavailable-SIAL204757-125G

Titanium(IV) oxide, Sigma-Aldrich®

Supplier: Merck
Description: Titanium(IV) oxide, Sigma-Aldrich®

Product Image-ACRO384292500

Titanium(IV) oxide, Aeroxide® P25

Supplier: Thermo Fisher Scientific
Description: Titanium(IV) oxide, Aeroxide® P25

MSDS

Image Unavailable-BOSSBS-12335R

Anti-HFE Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-12335R)
Supplier: Bioss
Description: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl
Image Unavailable-12286.36

Chromium(III) oxide 98+%, powder -325 Mesh

Supplier: Thermo Fisher Scientific
Description: It is employed in metallurgical processing and has applications in chrome plating, anodizing aluminum etc... It is also used as a pigment.

MSDS Certificates

Product Image-BOSSBS-2990R

Anti-CITED1 Rabbit Polyclonal Antibody

Catalog Number: (BOSSBS-2990R)
Supplier: Bioss
Description: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
UOM: 1 * 100 µl
Product Image-PRSI26-197

Anti-IMPG2 Rabbit Polyclonal Antibody

Catalog Number: (PRSI26-197)
Supplier: ProSci Inc.
Description: Interphotoreceptor matrix proteoglycan-2 (IMPG2) is part of an extracellular complex occupying the interface between photoreceptors and the retinal pigment epithelium in th e fundus of the eye.Interphotoreceptor matrix proteoglycan-2 is part of an extracellular complex occupying the interface between photoreceptors and the retinal pigment epithelium in the fundus of the eye.
UOM: 1 * 50 µG
Product Image-PRSI28-763

Anti-MITF Rabbit Polyclonal Antibody

Catalog Number: (PRSI28-763)
Supplier: ProSci Inc.
Description: MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
UOM: 1 * 100 µG
Image Unavailable-SIAL224227-100G

Titanium(IV) oxide rutile, Sigma-Aldrich®

Supplier: Merck
Description: Titanium(IV) oxide rutile, Sigma-Aldrich®

Image Unavailable-SIAL52468-1MG-F

C-Phycocyanin

Supplier: Merck
Description: C-Phycocyanin (CPC) is a pigment-protein complex from the light-harvesting phycobiliprotein family, it can be used in immunoassay kit development and to study its properties as a light harvesting protein.

Image Unavailable-BOSSBS-12335R-HRP

Anti-HFE Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-12335R-HRP)
Supplier: Bioss
Description: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl
Product Image-PRSI56-536

Anti-MLPH Rabbit Polyclonal Antibody

Catalog Number: (PRSI56-536)
Supplier: ProSci Inc.
Description: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
UOM: 1 * 400 µl

New Product


Image Unavailable-BOSSBS-2990R-HRP

Anti-CITED1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-2990R-HRP)
Supplier: Bioss
Description: Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0548R-HRP

Anti-MERTK Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (BOSSBS-0548R-HRP)
Supplier: Bioss
Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
UOM: 1 * 100 µl
Image Unavailable-SIAL635057-1EA

Titanium(IV) oxide, Sigma-Aldrich®

Catalog Number: (SIAL635057-1EA)
Supplier: Merck
Description: Titanium(IV) oxide, Sigma-Aldrich®
UOM: 1 * 1 items
Product Image-PRSI28-601

Anti-VAX1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI28-601)
Supplier: ProSci Inc.
Description: Vax1 is required for axon guidance and major tract formation in the developing forebrain. It may contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
UOM: 1 * 50 µG
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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