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Catalog Number: (BOSSBS-12335R-A488)
Supplier: Bioss
Description: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl


Catalog Number: (BOSSBS-12335R-CY3)
Supplier: Bioss
Description: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl


Supplier: Merck
Description: Copper(II) phthalocyanine, Sigma-Aldrich®

Catalog Number: (SIAL635057-1EA)
Supplier: Merck
Description: Titanium(IV) oxide, Sigma-Aldrich®
UOM: 1 * 1 items


Supplier: Merck
Description: Titanium(IV) oxide, Sigma-Aldrich®

Catalog Number: (SIAL702854-500MG)
Supplier: Merck
Description: Copper(II) phthalocyanine, Sigma-Aldrich®
UOM: 1 * 500 mg


Catalog Number: (BOSSBS-12335R-HRP)
Supplier: Bioss
Description: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl


Supplier: MP Biomedicals
Description: Ammonium bicarbonate is used in the manufacture of porous plastics, ceramics, dyes, and pigments, fire extinguishers. It has been used in the preparation and isolation of neoglycoprotein conjugates.
Supplier: Endress+Hauser
Description: Memosens 2.0 ISFET pH sensor for polluted media in chemical processes, paper or pigment production.

Catalog Number: (PRSI28-601)
Supplier: ProSci Inc.
Description: Vax1 is required for axon guidance and major tract formation in the developing forebrain. It may contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
UOM: 1 * 50 µG


Supplier: Merck
Description: Titanium(IV) oxide anatase, Sigma-Aldrich®

Catalog Number: (BRND61750)
Supplier: Brand
Description: This self-adhesive crepe indicator tape turns from white to brown upon autoclaving.
UOM: 1 * 1 items

Supplier: Merck
Description: Titanium(IV) oxide anatase, Sigma-Aldrich®

Supplier: Whatman products (Cytiva)
Description: These syringe filters, with pigment-free PP housing, are ideal for use with samples that require inorganic ion analysis, as levels of ion extractables are minimised.

Catalog Number: (PRSI25-378)
Supplier: ProSci Inc.
Description: Vax1 is required for axon guidance and major tract formation in the developing forebrain. Vax1 may contribute to the differentiation of the neuroretina, pigmented epithelium and optic stalk.
UOM: 1 * 50 µG


Supplier: Merck
Description: Copper(II) phthalocyanine, Sigma-Aldrich®

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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