You Searched For: Culture+Tubes

Description: The clear 1,5 mm thick polycarbonate shield offers impact and splash protection. Designed specifically for laboratory applications.

Catalog Number: 113-2800

UOM: 1 * 1 items

Supplier: Thermo Fisher Scientific

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Description: PC visor with PP browguard, is manufactured from impact resistant PP.

Catalog Number: PRTWPW91CLR

UOM: 1 * 1 items

Supplier: Portwest

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Description: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Catalog Number: BOSSBS-1312R-CY7

UOM: 1 * 100 µl

Supplier: Bioss

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Description: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Catalog Number: BOSSBS-1312R-HRP

UOM: 1 * 100 µl

Supplier: Bioss

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Description: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Catalog Number: BOSSBS-1312R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Catalog Number: BOSSBS-8542R-CY5

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Catalog Number: BOSSBS-8542R-CY3

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Catalog Number: BOSSBS-8542R-A350

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerises with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognises large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Catalog Number: BOSSBS-8542R-A680

UOM: 1 * 100 µl

Supplier: Bioss

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Description: Panoramic wrap-around visor for Height Endurance helmets range. It allows the user to wear over prescription glasses.

Catalog Number: PRTWPA03CLR

UOM: 1 * 1 items

Supplier: Portwest

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Description: Outer lens for the BizWeld Plus Welding Helmet.

Catalog Number: PRTWPW66CLR

UOM: 1 * 5 items

Supplier: Portwest

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Description: The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

Catalog Number: PRSI28-337

UOM: 1 * 100 µG

Supplier: ProSci Inc.

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Description: Biological sterilisation indicators are used to perform sterilisation cycle validation. They are created by inoculating spore suspensions of certified population and resistance onto paper strips.

Catalog Number: NAMSPM-106

UOM: 1 * 100 items

Supplier: CROSSTEX

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Description: These watches, with luminous dials, are ideal for use in industry, laboratories and for athletes. Once the special dial has been 'charged' with light (takes approx. 1 hour), the face will glow in the dark for approx. 3 to 4 hours so it is clearly readable. This requires no additional energy or radiating materials. This is achieved by using an innovative plastic material containing light-storing pigments.

Catalog Number: 609-1115

UOM: 1 * 1 items

Supplier: HANHART

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Description: Visor adapter for combination with the uvex pheos alpine safety helmets, Face shield

Catalog Number: 111-1942

UOM: 1 * 1 items

Supplier: UVEX

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Description: Chk2 is a serine/threonine kinase involved in the control of cell cycle checkpoints, and may also participate in transduction of the DNA damage and replicational stress signals. Chk2 is the mammalian ortholog of the budding yeast Rad53 and fission yeast Cds1 checkpoint kinases. The amino-terminal domain of Chk2 contains a series of seven serine and threonine residues (Ser19, Thr26, Ser28, Ser33, Ser35, Ser50 and Thr68) followed by glutamine (SQ or TQ motif). These are known to be preferred sites for phosphorylation by ATM/ATR kinases. Indeed, after DNA damage by ionizing radiation (IR), UV irradiation or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. Phosphorylation at Thr68 is a prerequisite for the subsequent activation step, which is attributable to autophosphorylation of Chk2 on residues Thr383 and Thr387 in the activation loop of the kinase domain. Chk2 inhibits CDC25C phosphatase by phosphorylating it on Ser-216, preventing the entry into mitosis. This kinase may have a role in meiosis as well. Kinase activity is up regulated by autophosphorylation and the protein is rapidly phosphorylated in response to DNA damage and to replication block.

Catalog Number: BOSSBS-4000R-A680

UOM: 1 * 100 µl

Supplier: Bioss

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