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Product Image-WITG0.133.019

Clips for spherical ground glass joints

Description: Very strong clips for spherical ground glass joints, made of stainless steel. With screw.
Catalog Number: WITG0.133.019
UOM: 1 * 1 items
Supplier: witeg Labortechnik
Image Unavailable-BOSSBS-1733R-FITC

Anti-MET Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.
Catalog Number: BOSSBS-1733R-FITC
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0668R-A555

Anti-MET Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.
Catalog Number: BOSSBS-0668R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-0668R-HRP

Anti-MET Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.
Catalog Number: BOSSBS-0668R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-MMME9132

Tegaderm™ Antimicrobial I.V. Advanced Securement Dressing

Description: <p>The Tegaderm™ Antimicrobial I.V. Advanced Securement Dressing is a peripheral IV securement dressing with chlorhexidine gluconate (CHG) formulated into the dressing adhesive. Its integrated design combines antimicrobial protection with site visibility, catheter securement and consistent application for peripheral IVs.</p>
Catalog Number: MMME9132
UOM: 1 * 25 items
Supplier: 3M MEDICAL

New Product


Product Image-525-0799

Centrifuge tubes, Eppendorf® Tubes 5,0 ml

Description: High quality polypropylene, transparent.
Catalog Number: 525-0799
UOM: 1 * 10 items
Supplier: EPPENDORF

Environmentally Preferable


Product Image-181-1007

Accessories for vacuum controller, vacuubrand

Description: Installation kit for CVC 3000, consists of 3 spring clips plus screws
Catalog Number: 181-1007
UOM: 1 * 1 items
Supplier: VACUUBRAND
Image Unavailable-BOSSBS-7533R-CY3

Anti-LPIN1 Rabbit Polyclonal Antibody (Cy3®)

Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
Catalog Number: BOSSBS-7533R-CY3
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-7533R-HRP

Anti-LPIN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
Catalog Number: BOSSBS-7533R-HRP
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-7533R-A488

Anti-LPIN1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.
Catalog Number: BOSSBS-7533R-A488
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-BOSSBS-7548R-A555

Anti-FGA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Description: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
Catalog Number: BOSSBS-7548R-A555
UOM: 1 * 100 µl
Supplier: Bioss
Image Unavailable-731-0503

Accessories for Boekel hybridisation apparatus

Description: Clips for holding 15 ml tubes in multi-tube carousel
Catalog Number: 731-0503
UOM: 1 * 50 items
Supplier: BOEKEL SCIENTIFIC
Product Image-201-0565

Joint clips for spherical joints, metal, Quickfit®

Description: Metal, corrosion resistant nickel finish. Clips in 'fork' type design for retaining glassware having Quickfit® spherical joints.
Catalog Number: 201-0565
UOM: 1 * 5 items
Supplier: SciLabware
Product Image-CONTSC-4

Cleaning swabs, double-ended, CONSTIX® SC-4

Description: SC-4 consists of high quality, long staple length cotton, tightly wrapped and shaped on both ends of high strength, wound paper handles.
Catalog Number: CONTSC-4
UOM: 1 * 5.000 items
Supplier: CONTEC
Product Image-229-0401

Tubing and wire clips, Klik Klip™, SP Bel-Art

Description: These clips neatly hold 6,5 mm (¼") diameter or smaller computer wires and tubing making identification and service easier.
Catalog Number: 229-0401
UOM: 1 * 6 items
Supplier: Bel-Art Products, a Part of SP
Image Unavailable-BNC881075-500

Anti-S100A9 Mouse Monoclonal Antibody (CF488A) [clone: S100A9/1075]

Description: This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
Catalog Number: BNC881075-500
UOM: 1 * 500 µl
Supplier: Biotium
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