You Searched For: ProSci Inc.

Catalog Number: (PRSI29-999)

Supplier: ProSci Inc.

Description: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

UOM: 1 * 100 µG

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Catalog Number: (PRSI30-058)

Supplier: ProSci Inc.

Description: PLP2 may play a role in cell differentiation in the intestinal epithelium.

UOM: 1 * 100 µG

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Catalog Number: (PRSI39-861)

Supplier: ProSci Inc.

Description: Cavin 3 SRBC (Serum deprivation response factor-related gene product that binds to C-kinase) is a member of PKCdelta-binding protein. Immunolocalization studies show Cavin 3 in caveoli. Cavin 3 appears to be recruited to caveoli by Cavin 1 and 2 where it forms a complex.

UOM: 1 * 100 µG

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Catalog Number: (PRSI39-869)

Supplier: ProSci Inc.

Description: Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.

UOM: 1 * 100 µG

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Catalog Number: (PRSI39-867)

Supplier: ProSci Inc.

Description: Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins

UOM: 1 * 50 µG

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Catalog Number: (PRSI39-873)

Supplier: ProSci Inc.

Description: STIM-1 is a component of the Ca sensor/channel. It associates with ORAI-1 and form a essential complex involved in store-operated channels. STIM1 activates Ca(2+) influx via Orai1 channels. Expression of STIM and Orai proteins are found in many cell types and knock-out mice lack viability.

UOM: 1 * 100 µG

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Catalog Number: (PRSI39-866)

Supplier: ProSci Inc.

Description: Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins

UOM: 1 * 50 µG

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Catalog Number: (PRSI39-860)

Supplier: ProSci Inc.

Description: Cavin 2-SDR (serum deprivation response) is a member of the PKC enzyme family. Immunolocalization studies show Cavin 2 in caveoli. Cavin 2 appears to be recruited to caveoli by Cavin 1. Cavin 2 appears to be involved in some aspects of caveolar function yet to be determined

UOM: 1 * 100 µG

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Catalog Number: (PRSI37-144)

Supplier: ProSci Inc.

Description: Anti-TNFSF11 Rat Monoclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI45-777)

Supplier: ProSci Inc.

Description: Anti-ITGB5 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI29-411)

Supplier: ProSci Inc.

Description: CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly (A) polymerase and other factors to bring about cleavage and poly (A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.

UOM: 1 * 50 µG

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Catalog Number: (PRSI29-397)

Supplier: ProSci Inc.

Description: SNRPD1 is a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA.This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA.

UOM: 1 * 50 µG

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Catalog Number: (PRSI29-407)

Supplier: ProSci Inc.

Description: HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Multiple alternative transcript variants seem to be present for this gene and some appear to have intronic regions in the mRNA. Presently, only two transcript variants are fully described.

UOM: 1 * 100 µG

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Catalog Number: (PRSI45-749)

Supplier: ProSci Inc.

Description: Anti-HSD3B1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

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Catalog Number: (PRSI30-725)

Supplier: ProSci Inc.

Description: ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.

UOM: 1 * 100 µG

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Catalog Number: (PRSI30-741)

Supplier: ProSci Inc.

Description: ZNF562 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 8 C2H2-type zinc fingers and 1 KRAB domain. ZNF562 may be involved in transcriptional regulation.

UOM: 1 * 50 µG

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