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Catalog Number: (478-3180)
Supplier: Air Liquide
Description: Protective visor, cryogenic, Protective visor, Colour (visor): Clear
UOM: 1 * 1 items


Catalog Number: (BSBTPB10001)
Supplier: Boster Bio
Description: DDAH2 is known as dimethylarginine dimethylaminohydrolase 2 which is mapped to 6p21.3 by radiation hybrid and FISH analysis. This gene encodes a dimethylarginine dimethylaminohydrolase. DDAH2 functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants.
UOM: 1 * 100 µG


Catalog Number: (PRSI92-045)
Supplier: ProSci Inc.
Description: Thioredoxin (TXN) is a member of the Thioredoxin family. Thioredoxin exists as a disulfide-linked homodimer and contains one Thioredoxin domain. Thioredoxin is up-regulated by ionizing radiation. Thioredoxin participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin also plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide.
UOM: 1 * 50 µG


Catalog Number: (531-0182)
Supplier: BUCHI
Description: Protective shield for heating bath B-491, for evaporator R-210 / R-215, For: Rotavapor® R-210 / R-215
UOM: 1 * 1 items


Catalog Number: (611-5824)
Supplier: Sartorius Balances
Description: The modular weighing system Cubis® II can be individually configured from different components. The combinability of the display unit, weighing module, draft shield, software packages for various applications and functions and a comprehensive range of accessories allows the individual adaptation of the Cubis® II balance to all weighing tasks.
UOM: 1 * 1 items

New Product


Catalog Number: (PRSI79-488)
Supplier: ProSci Inc.
Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
UOM: 1 * 100 µG


Supplier: WATERS
Description: XBridge™ BEH Shield RP18 columns complement the XBridge™ BEH C18 and C8 phases and provide a necessary and powerful tool for HPLC method development. The embedded carbamate group in the bonded phase ligand provides alternate selectivity, especially for phenolic compounds compared to straight chain alkyl columns.

Catalog Number: (WART2.000.600)
Supplier: WARTEWIG
Description: Draft shield, For: Flame 100
UOM: 1 * 1 items


Catalog Number: (MMMAET117015X16.5)
Supplier: 3M
Description: 3M™ EMI Shielding Tape 1170 is an easily die-cut, solderable 0,05 mm aluminium foil tape with conductive adhesive for EMI shielding and static charge draining when grounded. Acrylic adhesive has good resistance to heat, oxidation, solvents, and oils. Aluminum is an alternative conductive backing material to copper.
UOM: 1 * 1 Roll


Supplier: BD Medical
Description: The BD Vacutainer® Eclipse™ blood collection needle is a safety-engineered, multi-sample blood collection needle that offers a simple, effective way to collect blood while reducing the possibility of needlestick injuries. It features a safety shield that allows for one-handed activation to cover the needle immediately upon withdrawal from the vein and confirms proper activation with an audible click.

Catalog Number: (DELPVISORTOIN)
Supplier: DELTA PLUS
Description: Clear polycarbonate injected visor with electric arc protection. Suitable for face shield holder VISOR HOLDER and VIROR H (BALBI2 and PICO2 support). Ideal for forest work, building and construction and cutting applications.
UOM: 1 * 1 items


Catalog Number: (HEWL19256-80030)
Supplier: Agilent
Description: FPD is designed with minimum detectable levels of 3,6 pg/s for sulfur and 60 fg/s for phosphorus.
UOM: 1 * 1 items


Catalog Number: (BSANBS-040110-AAA)
Supplier: BIOSAN
Description: Operation principleis based on a constant, forced air circulation through recirculator's chamber in close vicinity to UV lamps, thusensuring maximalefficiency of disinfection. Theinner mirror surface of recirculator chamber reflects ultraviolet rays thereby increasing the density of UV radiation and enhancing the disinfection effect.
UOM: 1 * 1 items

New Product


Catalog Number: (BOSSBS-3948R)
Supplier: Bioss
Description: Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.
UOM: 1 * 100 µl


Catalog Number: (PRSI55-526)
Supplier: ProSci Inc.
Description: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.
UOM: 1 * 400 µl

New Product


Catalog Number: (BOSSBS-8355R)
Supplier: Bioss
Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'-linked polyubiquitination. Cooperates with the E2 CDC34 and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Ubiquitin chain elongation is then performed by CDC34, building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. Acts also as an initiator E2, in conjunction with RNF8, for the priming of PCNA. Monoubiquitination of PCNA, and its subsequent polyubiquitination, are essential events in the operation of the DNA damage tolerance (DDT) pathway that is activated after DNA damage caused by UV or chemical agents during S-phase. Associates with the BRCA1/BARD1 E3 ligase complex to perform ubiquitination at DNA damage sites following ionizing radiation leading to DNA repair. Targets DAPK3 for ubiquitination which influences promyelocytic leukemia protein nuclear body (PML-NB) formation in the nucleus. In conjunction with the MDM2 and TOPORS E3 ligases, functions ubiquitination of p53/TP53. Supports NRDP1-mediated ubiquitination and degradation of ERBB3 and of BRUCE which triggers apoptosis. In conjunction with the CBL E3 ligase, targets EGFR for polyubiquitination at the plasma membrane as well as during its internalization and transport on endosomes. In conjunction with the STUB1 E3 quality control E3 ligase, ubiquitinates unfolded proteins to catalyze their immediate destruction.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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