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Product Image-PRSI5605

Anti-LIN28 Rabbit Polyclonal Antibody

Catalog Number: (PRSI5605)
Supplier: ProSci Inc.
Description: Lin28 Antibody: Lin28 is a transcription factor that was first identified through its key role in the pathway of developmental timing in C. elegans. The role of Lin28 in development suggested that it might be useful in the creation of stem cells that might be beneficial in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing Lin28 in addition to the transcription factors POU5F1, Sox2, and NANOG in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing Lin28, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
UOM: 1 * 100 µG
Product Image-PRSI5581

Anti-POU5F1 Rabbit Polyclonal Antibody

Catalog Number: (PRSI5581)
Supplier: ProSci Inc.
Description: POU5F1 Antibody: POU5F1, also commonly known as Oct-4, is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. The role of POU5F1 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing POU5F1, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
UOM: 1 * 100 µG
Product Image-PRSI5585

Anti-NANOG Rabbit Polyclonal Antibody

Catalog Number: (PRSI5585)
Supplier: ProSci Inc.
Description: NANOG Antibody: Expression of NANOG is required for the maintenance of pluripotency in epiblast and embryonic stem (ES) cells as well as for the ability to maintain ES self-renewal independently of LIF/Stat3. The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
UOM: 1 * 100 µG
Product Image-442-1314

Magnetic hotplate stirrer, RCT basic

Catalog Number: (442-1314)
Supplier: IKA
Description: The RCT basic magnetic stirrer provides reliability, an exceptionally long product lifetime and the highest safety standards. RCT basic is suitable for stirring tasks up to 20 L (H₂O) and reaches temperatures up to 310 °C. With the connection option for an external temperature sensor (PT1000.60), the temperature can be measured and controlled directly in the reaction medium. Thanks to insulation of the aluminium heating plate, maintenance-free EC motor and electronic switching power supply, RCT basic features excellent energy efficiency as well as reduced self-heating of the heating plate during stirring operation, contributing to a more sustainable laboratory.
UOM: 1 * 1 items
Product Image-PRSI5603

Anti-KLF4 Rabbit Polyclonal Antibody

Catalog Number: (PRSI5603)
Supplier: ProSci Inc.
Description: KLF4 Antibody: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.
UOM: 1 * 100 µG
Product Image-710-1681

Petri dish filling systems, PetriSwiss PS200 and PS400

Supplier: BioTool
Description: PetriSwiss PS 200 and 400 automatically fill and stack Petri dishes in removable safety racks. The unit takes the lowest dish from the stack and places the dish, separated from its lid, into the UV-protected filling chamber. While filling the dish, the unit simultaneously stacks the previously filled dish and prepares the next dish to be filled. As soon as one PetriRack is processed completely, the unit moves the whole carousel by one position and restarts the process until all columns are processed. The unit stops after one full round to allow replacement of all dishes manually or with prefilled racks. This unique removable rack principle means that racks can be prefilled and loaded onto the rack carousel at any time. The dishes can remain stored in the rack, in a safe and stable stand. The unit downtime for refill is minimal. The PS 400 is supplied complete with 400 dish capacity carousel.

Product Image-PRSIPM-6141

Anti-KLF4 Mouse Monoclonal Antibody [clone: 4G6E11 ]

Catalog Number: (PRSIPM-6141)
Supplier: ProSci Inc.
Description: KLF4 Monoclonal Antibody: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.
UOM: 1 * 100 µG
Product Image-PRSIPM-6142

Anti-KLF4 Mouse Monoclonal Antibody [clone: 4E5C3 ]

Catalog Number: (PRSIPM-6142)
Supplier: ProSci Inc.
Description: KLF4 Monoclonal Antibody: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.
UOM: 1 * 100 µG
Product Image-611-2065

Industrial scales, Excellence Plus XP series

Catalog Number: (611-2065)
Supplier: Mettler - Toledo
Description: The large platform versions of XP balances provide fast, stable results, safety and security, making the range particularly suitable where regulatory compliance is required for high capacity weighing. The design features MonoBloc <sup>HighSpeed </sup>technology, a large, colour, backlit touch screen that facilitates direct access to all functions and an extended range of applications that include density determinations, formulation, piece counting, statistics and dynamic weighing. Commercial keyboards or barcode readers can be easily connected with the PS/2 interface option or connectivity can be extended to networks with optional interfaces for Ethernet and Bluetooth®.
UOM: 1 * 1 items
Product Image-113-1620

Overalls, Spacel 2000 EBJ, PE

Supplier: HONEYWELL SAFETY
Description: This overall made from PE features hood and zip and offers protection from low risks in a work environment, e.g. from harmful substances whose effects can be eliminated (cleaning products which are not too aggressive, diluted detergents etc.) or poor weather or for industrial cleaning operations.

Product Image-665-0566

Multiparameter Handheld Liquiline Mobile, CML18

Supplier: Endress+Hauser
Description: Liquiline Mobile CML18 is a mobile multi-parameter handheld device for measuring various parameters (pH, oxygen, conductivity). Thanks to Memosens technology, sensors for the different parameters can be connected via inductive coupling (plug and play).

Image Unavailable-HUBE2061.0001.01

Immersion thermostats

Supplier: HUBER
Description: Immersion thermostats form the basis of many different combinations with polycarbonate or stainless steel bath vessels. All models are fitted with a powerful pressure/suction pump and meet the requirements of Safety Class III (FL) for use with flammable fluids. Temperatures down to −30 °C can be achieved in combination with a refrigerated bath. A screw clamp is included allowing the thermostats to be easily mounted on any vessels. A pump adapter for external temperature control and cooling coils for a cooling water connection are available as optional accessories.

Product Image-705-2044

Dry block thermostat for cuvettes, LT 200

Supplier: Hach
Description: A digestion step often has to be carried out before key parameters can be determined. For these parameters, the LT 200 thermostat complements the LANGE cuvette test system. Two separately controllable heating blocks enable cuvettes and reaction vessels to be digested at identical or different temperatures and time settings. The LT 200 has a digital timer with an automatic switch-off and acoustic signal. Two transparent splash protection lids cover the thermostat while it is heating. The integrated over-temperature feature and the insulated external casing provide additional safety.

Product Image-462-0215

VWR®, Heating Circulators

Supplier: VWR Collection
Description: Stainless steel circulating baths with choice of Advanced Programmable or Advanced Digital temperature controller. Both are easy to navigate with large, intuitive displays and multiple communication options including USB-A and B, RS232/485, Ethernet and external temperature probe. The reservoir drain can be accessed by removing the front panel. All models feature user-adjustable high temperature safety cut-off points as well as over-temperature protection. The DuraTop™ surface is cool to the touch even when operating at high temperatures.

Product Image-611-2013

Semi-micro and analytical balances, Excellence Plus XP series

Supplier: Mettler - Toledo
Description: The XP analytical balances provide high performance weighing with improved linearity safety and security. This is achieved with the introduction of QM toolbox, SmartSens and MinWeigh functions alongside the SmartGrid technology, which provide fast and accurate weighing. This range is therefore particularly suited where regulatory compliance is required. The draught shield and drip tray can be completely, quickly and easily removed as before but now SmartSens allows the operator to weigh without touching the balance, thereby smoothing the work-flow and reducing spillage and contamination risks. MinWeigh warns the user if the minimum weight requirement, as laid down in USP or local GMP procedures, has been violated. The design also features a large, colour, backlit touch screen that facilitates direct access to all functions and an extended range of applications that include density determinations, differential weighing formulation, target weighing and statistical evaluation.

Product Image-111-1905

Earmuffs, uvex K2H

Catalog Number: (111-1905)
Supplier: UVEX
Description: These earmuffs for helmet mounting are suitable for use in medium noise areas (33 dB). They can be attached to the following uvex safety helmets: uvex pheos B-WR, uvex pheos alpine, uvex airwing and uvex superboss (additional adapter systems for combination with safety helmets and visors available on request). Two models are specifically designed for use with the uvex pheos helmet system.
UOM: 1 * 1 items
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at +43 1 97002 - 0.
Dual use goods can only be delivered within the European Union.
Dual use goods can only be delivered within the European Union.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at +43 1 97002 - 0.
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