You Searched For: STEMCELL Technologies

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2a antibody against mouse CD19, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Description: Leukemia inhibitory factor (LIF) is an interleukin 6 class cytokine that regulates a broad variety of developmental functions. After LIF binds to the LIF receptor (LIFR), LIFR associates with gp130 and activates JAK/STAT and MAPK signaling (Auernhammer and Melmed; Suman <i>et al.</i>). LIFR activation of STAT3 is essential for maintaining the mouse embryonic stem cell phenotype (Niwa <i>et al.</i>). Produced by the endometrium, LIF plays an important autocrine and paracrine role in implantation by regulating proliferation, invasion, and differentiation of trophoblasts following blastocyst attachment (Auernhammer and Melmed; Suman <i>et al.</i>). Human LIF can be used for the maintenance of mouse embryonic stem cells; however, mouse LIF cannot bind to the human receptor, thus rendering mouse LIF inactive (Dahéron <i>et al.</i>). LIF is produced by CD4+ and activated regulatory T cells, and promotes Foxp3 expression, while repressing Th17 lineage-specific genes (Metcalfe). LIF is also secreted by mesenchymal stromal cells, where it supports hematopoiesis and immune modulation (Nasef <i>et al.</i>).

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1, kappa isotype control antibody, PE-conjugated.

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b antibody against mouse CD16/CD32, FITC-conjugated.

Supplier: STEMCELL Technologies

Description: Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family. Noggin supports maintenance of undifferentiated human embryonic stem cells in vitro, and can be used to prevent spontaneous differentiation in the short term (Chaturvedi <i>et al.</i>). Noggin is essential for development of structures derived from ectoderm embryonic somite, skeletal patterning, and neurogenesis in vivo. It also influences chondrogenesis, osteogenesis, and joint formation (Krause <i>et al.</i>), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba <i>et al.</i>).

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b, kappa isotype control antibody, PE-conjugated.

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, chimpanzee CD3, FITC-conjugated.

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD40, FITC-conjugated.

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG2b antibody against human, rhesus HLA-DR, FITC-conjugated.

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2a antibody against mouse, toad CD8a, FITC-conjugated.

Catalog Number: (STMC05707)

Supplier: STEMCELL Technologies

Description: Kit for chemical dissociation of mouse neurospheres.

UOM: 1 * 1 KIT

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Catalog Number: (STMC60053)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgM antibody against human, mouse, rat oligodendrocyte marker O4, unconjugated.

UOM: 1 * 50 µG

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Supplier: STEMCELL Technologies

Description: Immunomagnetic isolation of untouched mouse CD8+ T cells

Supplier: STEMCELL Technologies

Description: Interleukin 33 (IL-33) is a pro-inflammatory cytokine from the IL-1 family. It binds to ST2 receptor and activates NF-κB and MAPK pathways. IL-33 is expressed by epithelial cells, smooth muscle cells, and fibroblasts in various tissues and organs, as well as resting basophils, mast cells, eosinophils, natural helper cells, group 2 innate lymphoid cells, dendritic cells, and activated macrophages (Schmitz <i>et al.</i>; Yasuda <i>et al.</i>). It contributes to allergic inflammation by stimulating production of the cytokines IL-4, IL-5, and IL-13, and stimulates host defense against microbial and viral infections (Liew; Yasuda <i>et al.</i>). In the central nervous system, IL-33 is produced by endothelial cells and astrocytes. It induces proliferation of microglia and mediates production of pro-inflammatory cytokines (Yasuoka <i>et al.</i>).

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG2b antibody against human, mouse, rat GFAP (glial fibrillary acidic protein), unconjugated.

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2a antibody against mouse, toad CD8a, PE-conjugated.